Xiaomei Dai, Xuelei Chen, Jing Zhao, Yu Zhao, Qianqian Guo, Tianqi Zhang, Chunli Chu, Xinge Zhang, and Chaoxing Li.ACS Applied Materials & Interfaces 2017, 9
Enhanced Antibacterial Properties of Self-Assembling Peptide Amphiphiles Functionalized with Heparin-Binding Cardin-Motifs. Run Chang, Keerthana Subramanian, Mian Wang, and Thomas J.Solid-State NMR Investigations of Extracellular Matrixes and Cell Walls of Algae, Bacteria, Fungi, and Plants. Nader Ghassemi, Alexandre Poulhazan, Fabien Deligey, Frederic Mentink-Vigier, Isabelle Marcotte, Tuo Wang.This article is cited by 92 publications. The protein binding to the bacteria-wall surface would represent a first encounter step key in its antimicrobial mechanism of action. coli does not require any pretreatment to overcome the outer membrane barrier. Moreover, the depolarization activity on E. ECP also activates the cytoplasmic membrane depolarization in both strains. Although both bacteria strain cells retain their shape and no cell lysis is patent, the protein can induce in E. The protein damages the bacteria surface and induces the cell population aggregation on E. Ultrastructural analysis of cell bacteria wall and morphology have been visualized by scanning and transmission electron microscopy in both Escherichia coli and Staphylococcus aureus strains. The protein also binds in vivo to bacteria cells. ECP high-affinity binding capacity to LPSs and lipid A has been analyzed by a fluorescent displacement assay, and the corresponding dissociation constants were calculated using the protein labeled with a fluorophor. We have analyzed its specific association to lipopolysaccharides (LPSs), its lipid A component, and peptidoglycans (PGNs). We have now shown that ECP can bind with high affinity to the bacteria-wall components.
The protein can destabilize lipid bilayers, although the action at the membrane level can only partially account for its bactericidal activity. The protein displays antimicrobial activity against both Gram-negative and Gram-positive strains. We will see that God’s most precious gift to man, Time, provided Naville the ultimate measure of his moral worth.The eosinophil cationic protein (ECP) is an eosinophil-secreted RNase involved in the immune host defense, with a cytotoxic activity against a wide range of pathogens. He will situate Naville’s use of these tools within the Swiss pedagogical reform movement of Pestalozzi and others in the early nineteenth century and will examine in detail how Naville used and adapted Franklin and Jullien’s tools of moral accounting for his own moral and religious purposes. Harro Maas, professor in history and methodology of economics at the Centre Walras-Pareto for the history of economic and political thought at the University of Lausanne, will use these words from the diary of François-Marc-Louis Naville, a turn-of-the nineteenth-century Genevese pastor and pedagogical innovator, as a cue to examine his use of Benjamin Franklin’s tools of moral calculation and a lesser known tool, Marc-Antoine Jullien’s moral thermometer, to improve his moral character. I feel deeply that there is nothing more to be desired than what pertains to eternity, that I should not waste a moment of time, that I should hurry to fulfill at least part of my task.” A decrease in energy and health, though possibly only temporary, makes me nevertheless fear for an early death. I feel myself dragged about by time as if by a torrent.